Karl Lagerfeld has it out for Heidi Klum! In Round 2, the Kaiser goes after hubby Seal. Photos: Getty Images

Karl Lagerfeld is at it again! His first Heidi Klum diss appeared in February's German GQ, where the Chanel designer said "I don't know Heidi Klum. She was never known in France. Claudia Schiffer also doesn't know who she is."

Now, as reported by The Sun, Lagerfeld has gone after Klum's husband Seal, saying "I am no dermatologist, but I wouldn't want his skin."

No word from Heidi or Seal, but that cheap shot doesn't deserve a response.

What's behind these mean-spirited attacks on the German supermodel and now her musician husband?