The vintage-inspired tees are $50 each, with $25 going directly to CTAOP, which aims to create a better life for young people in South Africa, especially those living in remote regions with a high chance of contracting HIV.
Charlize Theron's Africa Outreach Project will put the money raised toward helping to provide sustainable health care, education and recreational outlets, including soccer fields, in these areas.
The four styles feature either the South African Baobab tree scrawled with CTAOP's motto: "Look Within, Think Beyond and Reach Out" or the CTAOP logo (three multicolored loops encircling a sphere); available in grey, white, purple, pink and orange.
"Give and Take is a socially responsible company and I'm thrilled to have their support," says Theron. "The kids that are being helped through my African Outreach Project are so incredible and vibrant. These t-shirts capture the spirit of South Africa and give everyone a way to help."
To support Theron's cause, go to giveandtaketees.com to pre-order your tee.