And while each of the men has his own style calling card -- Depp's aforementioned "eccentric cool" and Robert Pattinson's "best head of hair on the planet" -- the guys aren't ranked in any order. Instead, the magazine is asking readers to crown the most stylish man of all at GQ.com.
So, who's in the running for the #1 spot? (Try to keep the drool to a minimum.)
The actor/director/TV host category includes Ryan Gosling, Spike Jonze, Clint Eastwood, Brad Pitt, Anderson Cooper and cover star Depp, who seems to already have the vote of Barneys New York's Simon Doonan.
"Depp's a unicorn -- a really glamorous, one-of-a-kind eccentric," Doonan tells the magazine. "He wears great man jewelry. He doesn't shy away from color. He's always peeking through his amazing hair. It doesn't matter if Johnny Depp's lying in a ditch -- he's always going to look incredible."
GQ's musical candidates include Andre 3000, Pharrell Williams and Jay-Z (cue Kanye mic grab), while Lebron James and Tom Brady (whom the magazine says knows "the power of the rugged look") represent the sports category.
Although, as Brady explains, his supermodel wife Gisele Bündchen isn't always that into the scruffy style. "I think she likes the way the beard looks," he says "But she doesn't like the way it feels -- it pokes her face."
Aside from 13 Americans, eight Brits also made the cut, including Pattinson, Ed Westwick and David Beckham as did Portuguese soccer star/Emporio Armani Underwear model Cristiano Ronaldo.
Who do you think is the most stylish man in the world? Leave a comment with your vote!
And see which actress was just named the most desirable woman.