Of course, no one should be too surprised by Jacobs' sole inclusion, as he was the only designer on the ballot of 200 individuals, alongside other fashion industry luminaries, Anna Wintour and Tim Gunn, both of whom could have also made the list.
While Stella McCartney, who was the only designer to make the 2009 Time 100 list, was interviewed by pal Gwyneth Paltrow, this time around Jacobs was paired with Victoria Beckham, a client of his who has also appeared in his ads (who can forget her legs dangling out of an oversized MJ shopping bag?).
"He inspires and educates me every time we meet," Beckham says of Jacobs in the profile. "He changes how we see fashion with each collection he shows, be it his work for Louis Vuitton or his own baby, the Marc Jacobs line, which he started in 1986."
Although they weren't featured in the Top 100 themselves, a few other designers got their feet wet for the issue in other ways. Donna Karan interviews architect Zaha Hadid about her wondrous organic creations, Donatella Versace interviews Jet Li about their mutual efforts assisting Chinese earthquake victims and Tom Ford interviews model and activist Liya Kebede, whom he helped discover.
Everyone will have to wait until tomorrow to see if other attention-grabbing names on the ballot -- Lady Gaga and Snooki, anyone? -- made the list.
In the meantime, do you think there is a more influential designer than Jacobs right now? Let us know in a comment below.