Barricades and a white tent erected over the street greeted a small crowd of onlookers who turned out in the West Village to see the presidential motorcade arrive shortly after 7pm.
Security in the picturesque neighborhood -- just blocks from where Carrie Bradshaw and her friends nibbled cupcakes at Magnolia Bakery -- included a low-flying helicopter and armed units positioned on nearby rooftops.
Dinner guests are said to have included Donna Karan, Diane von Furstenberg, Vera Wang, Harvey Weinstein, hotelier André Balazs, and actress Kerry Washington.
Also in attendance was Calvin Klein, who co-hosted a 2008 fund-raiser with Wintour for then presidential candidate Obama and his wife, Michelle.
Vogue editor-at-large André Leon Talley attended both events and interviewed Michelle, who was now first lady, for a cover story in the magazine's March 2009 issue.
It was a busy day for the president, who began with a visit to a New Jersey sandwich shop before crossing the Hudson River to shoot an episode of "The View" with hosts Whoopi Goldberg, Barbara Walters, Joy Behar, Sherri Shepherd, and Elisabeth Hasselbeck.
The president also attended another $30,400-a-head fund-raiser at the Four Seasons Hotel during his visit to Manhattan. The fee, which benefits the Democratic National Committee, is the most an individual is permitted by law to donate to a political party in a two-year election cycle.
In other political news, read about Chelsea Clinton's wedding dress.